Sun-044 Plasmonic Fluor Provides Ultrasensitive Detection of Kidney Injury Biomarkers on Antibody Sandwich Microarrays
Year: 2020
Type: conference-abstract
Abstract: Detection and quantification of low abundant biomarkers within biological fluids is important but remains extremely challenging in biomedical research as well as clinical diagnostics. Here, we designed and synthesized an ultrabright fluorescent nanoconstruct, termed “plasmonic-fluor”, as an “add-on” label to dramatically improve the signal-to-noise ratio of a wide variety of fluorescence bioassays without altering or complicating the conventional assay workflow or read-out devices. Plasmonic-fluor is highly tunable over the entire visible and near infrared spectrum and up to 6500 times brighter than the conventional fluorophores.
Source: Kidney International Reports
Authors: J. Morrissey, J. Luan, S. Singamaneni
Institution: Washington University in St. Louis
Language: English
Field: Materials Science
Domain: Physical Sciences
Open Access status: gold
Estimated APC paid: $2,625
OpenAlex ID: W3011744174