The Multifaceted Role of Low Dose IV Ketamine to Control Debilitating Neuropathic Pain Conditions
Year: 2020
Type: article
Abstract: Ketamine has been around since the 1960s, providing analgesia, amnesia, hypnosis and has been used to treat acute pain, chronic pain, acute on chronic pain, neuropathic pain, refractory head pain, depression, and post-traumatic stress disorder (PTSD).Depression, posttraumatic-stress disorder, and chronic regional pain syndrome (CRPS), can all be extremely debilitating pathologies from a functional, emotional, and spiritual perspective.The mind, body, and spirit are all interconnected, and play a crucial role in the management of these medical conditions.Though oral medications have been used as a mainstay therapy, there can be some limitations with achieving therapeutic effects.Ketamine is a mixture of R-ketamine and S-ketamine, each demonstrating unique qualities in aiding treatment.Additional metabolism of R-ketamine and S-ketamine has resulted in distinctive metabolites providing treatment for depression, suicidal ideations, and complex regional pain syndrome.Intravenous ketamine administration has provided therapeutic effects for headaches refractory to standard therapy.The utilization of ketamine continues to evolve and continues to provide beneficial clinical treatments, with limited side effects.
Source: Internal Medicine Review
Authors: Nirmal Shah, Michael Sabia, Rajat Mathur, Michael Goldberg, Irving Wainer, Marc Torjman
Language: English
Subfield: Physiology
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W3011890195