Work

Econazole nitrate reversed the resistance of breast cancer cells to Adriamycin through inhibiting the PI3K/AKT signaling pathway.

Year: 2020

Type: article

Abstract: . Taken together, the PI3K inhibitor econazole could effectively overcome Adriamycin resistance and showed synergistic effects with chemotherapy on breast cancer.

Source: PubMed Central

Authors: Chao Dong, Yin Chen, Jing Ma, Runxiang Yang, Hongjian Li, Rong Liu, Dingyun You, Chunxiang Luo, Heng Li, Siyuan Yang, Kunbin Ke, Marie Chia-Mi Lin, Ceshi Chen

Institutions: Kunming Medical University, Second Military Medical University, Changhai Hospital, Kunming Children's Hospital, Chinese University of Hong Kong, Hong Kong Science and Technology Parks Corporation, Kunming Institute of Zoology, Chinese Academy of Sciences, First Affiliated Hospital of Kunming Medical University, Zhengzhou University

Language: English

Topic: PI3K/AKT/mTOR signaling in cancer

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W3012081230

FWCI: 1

Cites: 24

Cited by: 19

Related to: 10