Work

TLR4 activation leads to anti-EGFR therapy resistance in head and neck squamous cell carcinoma.

Year: 2020

Type: article

Abstract: . Out study delineates a crosstalk between EGFR and TLR4 pathways and identified TLR4 as a potential biomarker as well as a therapeutic target in overcoming the resistance to anti-EGFR therapy of HNSCC.

Source: PubMed Central

Authors: Houyu Ju, Zhenrong Hu, Yusheng Lu, Yunteng Wu, Liming Zhang, Dongliang Wei, Wei Guo, Weiya Xia, Shuli Liu, Guoxin Ren, Jingzhou Hu

Institutions: Shanghai Jiao Tong University, Shanghai Stomatological Hospital, Shanghai Ninth People's Hospital, The University of Texas MD Anderson Cancer Center

Language: English

Topic: Head and Neck Cancer Studies

Subfield: Otorhinolaryngology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W3012822845

FWCI: 3.32

Cites: 38

Cited by: 22

Related to: 10