Work

A Photocaged, Water-Oxidizing, and Nucleolus-Targeted Pt(IV) Complex with a Distinct Anticancer Mechanism

Year: 2020

Type: article

Source: Journal of the American Chemical Society

DOI: 10.1021/jacs.0c00221

Authors: Zhiqin Deng, Na Wang, Yingying Liu, Zoufeng Xu, Zhigang Wang, Tai-Chu Lau, Guangyu Zhu

Institutions: City University of Hong Kong, City University of Hong Kong, Shenzhen Research Institute, Shenzhen University, Shenzhen University Health Science Center

Language: English

Topic: Metal complexes synthesis and properties

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: closed

Funders: National Natural Science Foundation of China, Research Grants Council, University Grants Committee

Awards: Development and mechanistic investigation of nucleus-targeting platinum(IV) prodrugs for improved anticancer activity, Synthesis, mechanistic study, and biological evaluation of visible light-activatable platinum(IV) anticancer prodrugs, G569341042

OpenAlex ID: W3013235937

FWCI: 13.57

Cites: 51

Cited by: 243

Related to: 10