Work

Bowel Perforation in the Emergency Department Related to Bevacizumab Therapy and Recurrent Ovarian Cancer

Year: 2020

Type: article

Abstract: CASE PRESENTATION: We describe the presentation to the emergency department of a patient with recurrent ovarian cancer treated with bevacizumab with the complication of bowel perforation. DISCUSSION: We review the frequency and outcomes of bevacizumab-related bowel perforation. We also report the patient's imaging findings, including the radiologic presentation of free intraperitoneal air and portal venous gas, both indicative of bowel perforation and the need for emergent surgical evaluation. Our case also illustrates the potentially catastrophic side effects of bevacizumab and other targeted oncologic therapies of which emergecny physicians may not be aware.

Source: Clinical Practice and Cases in Emergency Medicine

DOI: 10.5811/cpcem.2020.1.45374

Authors: Stuart Ostby, Michael Olushoga, Charles Leath, Samuel Burleson

Institutions: University of Alabama at Birmingham, UAB Medicine

Language: English

Topic: Abdominal vascular conditions and treatments

Subfield: Surgery

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $500