Work

MicroRNA-92 regulates vascular smooth muscle cell function by targeting KLF4 during vascular restenosis and injury.

Year: 2019

Type: article

Abstract: , miR-92 overexpression promoted neointimal formation, and thus resulted in a dramatic increase in intimal-medial area and thickness. These results reveal that miR-92 regulates VSMC function by directly targeting KLF4, which may be an important finding useful for the diagnosis and treatment of vascular restenosis and injury, arteriosclerosis, and other proliferative vascular diseases.

Source: PubMed

Authors: Shuhao Deng, Yuan Zhang, Yongbing Wang, Xin Lu, Quan Jiang

Institutions: Shanghai University of Medicine and Health Sciences, Pudong New Area People's Hospital

Language: English

Topic: MicroRNA in disease regulation

Subfield: Cancer Research

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W3013587187

FWCI: 0.484

Cites: 41

Cited by: 12

Related to: 10