Year: 2020
Type: article
Abstract: Properly set sample size is one of the important factors for scientific and persuasive research. The sample size that can guarantee both clinically significant differences and adequate power in the phenomena of interest to the investigator, without causing excessive financial or medical considerations, will always be the object of concern. In this paper, we reviewed the essential factors for sample size calculation. We described the primary endpoints that are the main concern of the study and the basis for calculating sample size, the statistics used to analyze the primary endpoints, type I error and power, the effect size and the rationale. It also included a method of calculating the adjusted sample size considering the dropout rate inevitably occurring during the research. Finally, examples regarding sample size calculation that are appropriately and incorrectly described in the published papers are presented with explanations.
Source: Korean Journal of Anesthesiology
DOI: 10.4097/kja.19497
Institutions: Dongguk University Ilsan Hospital, Chung-Ang University, Daegu Catholic University, Daegu Catholic University Medical Center, Pusan National University Yangsan Hospital, Pusan National University, Inje University Seoul Paik Hospital, Korea University, Korea University Guro Hospital, Inje University, Inje University Sanggye Paik Hospital, Inje University Haeundae Paik Hospital
Language: English
Subfield: Statistics and Probability
Field: Mathematics
Domain: Physical Sciences
Open Access status: diamond
OpenAlex ID: W3013623720