Diet, Lifestyle and Cardiovascular Diseases: Linking Pathophysiology to Cardioprotective Effects of Natural Bioactive Compounds
Year: 2020
Type: review
Abstract: Heart and blood vessels disorders comprise one of the main causes of death worldwide. Pharmacologically active natural compounds have been used as a complementary therapy in cardiovascular disease around the world in a traditional way. Dietary, natural bioactive compounds, as well as healthy lifestyles, are considered to prevent coronary artery diseases. Pre-clinical and clinical studies reported that consumption of plant-food bioactive derivatives including polyphenolic compounds, peptides, oligosaccharides, vitamins, unsaturated fatty acids possess protective effects on cardiovascular diseases. This review aims to summarize the cardiovascular risk factors, pre-clinical studies and clinical trials related to cardioprotective properties of the plant-food-derived bioactive compounds. Molecular mechanisms by the natural bioactive compounds exert their cardiovascular protective properties have also been highlighted.
Authors: Javad Sharifi-Rad, Célia F. Rodrigues, Farukh Sharopov, Anca Oana Docea, Aslı Can Karaca, Mehdi Sharifi-Rad, Derya Kahveci Karıncaoglu, Gözde Gülseren, Ezgi Şenol, Evren Demircan, Yasaman Taheri, Hafiz Ansar Rasul Suleria, Beraat Özçelik, Kadriye Nur Kasapoğlu, Mine Gültekin-Özgüven, Ceren Daşkaya-Dikmen, William C. Cho, Natália Martins, Daniela Calina
Institutions: Zabol University of Medical Sciences, Universidade do Porto, Tajik State Medical University, University of Medicine and Pharmacy of Craiova, Istanbul Technical University, Kerman University of Medical Sciences, Shahid Beheshti University, Shahid Beheshti University of Medical Sciences, The University of Melbourne, Queen Elizabeth Hospital, i3S - Instituto de Investigação e Inovação em Saúde, Universidade do Porto
Language: English
Subfield: Biochemistry (medical)
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $2,429
OpenAlex ID: W3013754122