Work

Adding SNX to the mix: SNX9 drives filopodia biogenesis

Year: 2020

Type: article

Abstract: Filopodia are actin-rich protrusions important for sensing and responding to the extracellular environment, but the repertoire of factors required for filopodia formation is only partially understood. Jarsch et al. (2020. J. Cell. Biol. https://doi.org/10.1083/jcb.201909178) combine an in vitro system of filopodia biogenesis with a phage display screen to show that SNX9 drives filopodial assembly.

Source: The Journal of Cell Biology

DOI: 10.1083/jcb.202002086

Authors: Nadine M. Lebek, Kenneth G. Campellone

Institution: University of Connecticut

Language: English

Topic: Cellular Mechanics and Interactions

Subfield: Cell Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: hybrid

Funders: National Institutes of Health, National Institute on Aging, National Institute of General Medical Sciences

Awards: Cytoskeletal control of membrane remodeling, Cytoskeletal functions in cell aging and disease