Work

S1P1-selective agonist prodrug IMMH002 is phosphorylated in rats to form an S-configured enantiomer: Synthesis, verification, and biological activity of the in vivo active metabolite

Year: 2020

Type: article

Source: Bioorganic & Medicinal Chemistry Letters

DOI: 10.1016/j.bmcl.2020.127141

Authors: Qiong Xiao, Minwan Hu, Si Chen, Jing Jin, Li Li, Jinping Hu, Ping Xie, Dali Yin

Institutions: Chinese Academy of Medical Sciences & Peking Union Medical College, Institute of Chinese Materia Medica

Language: English

Topic: Sphingolipid Metabolism and Signaling

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: closed

Funders: Ministry of Science and Technology of the People's Republic of China, Chinese Academy of Medical Sciences

OpenAlex ID: W3013859078

FWCI: 0.081

Cites: 18

Cited by: 1

Related to: 10