Work

Long non-coding RNA HOXA11-AS upregulates Cyclin D2 to inhibit apoptosis and promote cell cycle progression in nephroblastoma by recruiting forkhead box P2.

Year: 2020

Type: article

Abstract: . Taken together, silencing of HOXA11-AS promotes apoptosis and inhibits the cell cycle entry in nephroblastoma by recruiting the transcription factor FOXP2 to downregulate the expression of CCND2, highlighting a promising novel direction for future nephroblastoma treatment.

Source: PubMed

Authors: Shibo Zhu, Jingqi Zhang, Yanhong Cui, Xiangliang Tang, Xiaofeng Gao, Dian Li, Wei Jia

Institutions: Jinan University, Guangzhou Women and Children Medical Center, First Affiliated Hospital of Jinan University, Guangzhou Medical University

Language: English

Topic: Cancer-related molecular mechanisms research

Subfield: Cancer Research

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W3013861488

FWCI: 1.187

Cites: 30

Cited by: 17

Related to: 10