A Novel Therapy for Huntington's Disease.
Year: 2018
Type: article
Abstract: In 1979, while at the National Institutes of Health, now Columbia University professor Nancy Wexler and colleagues traveled to Venezuela to study the world’s largest family with Huntington’s disease. That led to identifying the disease gene at the tip of human chromosome 4 and the race to find a drug that can treat people who carry the fatal gene prior to the onset of symptoms. Our author believes that a new strategy tied to turning off targeted genes could have profound implications for therapy development for Huntington’s and other neurodegenerative diseases.
Source: Europe PMC (PubMed Central)
Author: Albert R La Spada
Language: English
Subfield: Cellular and Molecular Neuroscience
Field: Neuroscience
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W3014099861