Work

PACAP neuropeptide promotes Hepatocellular Protection via CREB-KLF4 dependent autophagy in mouse liver Ischemia Reperfusion Injury

Year: 2020

Type: article

Abstract: : Current study documents the essential neural regulation of PACAP-promoted autophagy in hepatocellular homeostasis in OLT, which provides the emerging therapeutic principle to combat hepatic IRI in OLT.

Source: Theranostics

DOI: 10.7150/thno.42354

Authors: Zhengze Xue, Yu Zhang, Yuanxing Liu, Cheng Zhang, Xiu-da Shen, Feng Gao, Ronald W. Busuttil, Shusen Zheng, Jerzy W. Kupiec-Weglinski, Haofeng Ji

Institutions: University of California, Los Angeles, First Affiliated Hospital Zhejiang University, Zhejiang University

Language: English

Topic: Autophagy in Disease and Therapy

Subfield: Epidemiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,671

Funders: National Natural Science Foundation of China, National Institutes of Health, National Institute of Allergy and Infectious Diseases, National Institute of Diabetes and Digestive and Kidney Diseases

Awards: G2251898864, TIM-3 Negative Costimulation Signaling at the Innate-Adaptive Immune interface in Liver Transplant Ischemia-Reperfusion Injury, CEACAM1介导的TIM-3在肝脏窦内皮细胞缺血再灌注损伤过程中负向调节作用及其机制研究, Tim Costimulation in Liver Transplant Ischemia Injury, Ischemia / Reperfusion Injury Mediated TIM-3+CD4+ T Cell Exhaustion In Liver Transplant, PACAP Mediated Neural Regulation of Hepatic Inflammation in Orthotopic Liver Transplantation, G9000252277, Innate-Adaptive Immunoregulation in Liver Transplant Ischemia/Reperfusion Injury, HuR/HIF – SIRT1 Signaling Axis in Liver Transplant Rejuvenation

OpenAlex ID: W3015221583

FWCI: 2.686

Cites: 53

Cited by: 27

Related to: 10