Work

Role of Pseudomonas aeruginosa Glutathione Biosynthesis in Lung and Soft Tissue Infection

Year: 2020

Type: article

Abstract: The opportunistic pathogen Pseudomonas aeruginosa is a leading cause of morbidity and mortality worldwide. To survive in both the environment and the host, P. aeruginosa must cope with redox stress. In P. aeruginosa , a primary mechanism for protection from redox stress is the antioxidant glutathione (GSH). GSH is a low-molecular-weight thiol-containing tripeptide ( l -γ-glutamyl- l -cysteinyl-glycine) that can function as a reversible reducing agent.

Source: Infection and Immunity

DOI: 10.1128/iai.00116-20