Tunable Ultrahigh Dielectric Constant (tuHDC) Ceramic Technique to Largely Improve RF Coil Efficiency and MR Imaging Performance
Year: 2020
Type: article
Abstract: This work introduces an innovative magnetic resonance (MR) imaging technology that incorporates radiofrequency (RF) coil(s) with permittivity-tunable ultrahigh dielectric constant (tuHDC) ceramics to significantly improve RF coil transmission and reception efficiencies, MR imaging sensitivity and signal-to-noise ratio (SNR). The tuHDC ceramics made of composite barium strontium titanate (BST) compounds (Ba0.6Sr0.4TiO3) have low dielectric loss and very high permittivity tunability from 2,000 to 15000 by varying the ceramic temperature between 0°C and 40°C to achieve an optimal permittivity for MR imaging application. We demonstrated for the first time the proof of concept using the BST-based tuHDC-RF-coil technology to improve MR spectroscopic imaging performance of17O nuclide at 10.5 Tesla (T) at a low ceramic temperature and23Na nuclide at 7T at room temperature. We discovered a large and spatially independent noise reduction under an optimal ceramic temperature, which synergistically resulted in an unprecedented SNR improvement. Large improvements were also demonstrated for1H MRI on a 1.5T clinical scanner using the same ceramics. The tuHDC-RF-coil technology is robust, flexible and cost-effective; it presents a technical breakthrough to significantly improve imaging sensitivity and resolution for broad MR imaging applications; which is critical for advancing biomedical and neuroscience research, and improving diagnostic imaging.
Institutions: University of Minnesota, Pennsylvania State University
Language: English
Subfield: Radiology, Nuclear Medicine and Imaging
Field: Medicine
Domain: Health Sciences
Open Access status: green
Awards: Advancing MRI & MRS Technologies for Studying Human Brain Function and Energetics, CONSOLE FOR 10.5 TESLA WHOLE BODY MRI SYSTEM, Breaking Spatiotemporal Barriers of MR Imaging Technologies to Study Human Brain Function and Neuroenergetics, Integrated fMRI Methods to Study Neurophysiology and Circuit Dynamics at Laminar and Columnar Level, G8669681486, Technology to Realize the Full Potential of UHF MRI, Development of Quantitative Deuterium MRS Imaging for Human Brain Tumor Application at Ultrahigh Field
OpenAlex ID: W3016454123
