Year: 2020
Type: article
Abstract: In vivo proton magnetic resonance spectroscopy and spectroscopic imaging (MRS/MRSI) are valuable tools to study normal and abnormal human brain physiology. However, they are sensitive to motion, due to strong crusher gradients, long acquisition times, reliance on high magnetic field homogeneity, and particular acquisition methods such as spectral editing. The effects of motion include incorrect spatial localization, phase fluctuations, incoherent averaging, line broadening, and ultimately quantitation errors. Several retrospective methods have been proposed to correct motion-related artifacts. Recent advances in hardware also allow prospective (real-time) correction of the effects of motion, including adjusting voxel location, center frequency, and magnetic field homogeneity. This article reviews prospective and retrospective methods available in the literature and their implications for clinical MRS/MRSI. In combination, these methods can attenuate or eliminate most motion-related artifacts and facilitate the acquisition of high-quality data in the clinical research setting.
Source: Magnetic Resonance in Medicine
DOI: 10.1002/mrm.28287
Language: English
Subfield: Radiology, Nuclear Medicine and Imaging
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
Funders: National Institutes of Health, National Institute on Aging, National Institute on Drug Abuse, National Institute of Neurological Disorders and Stroke, National Institute of Biomedical Imaging and Bioengineering, National Center on Minority Health and Health Disparities, National Center for Research Resources, National Institute on Minority Health and Health Disparities, Eunice Kennedy Shriver National Institute of Child Health and Human Development
Awards: G1140538806, RGR-based motion tracking for real-time adaptive MR imaging and spectroscopy, G1244017850, G1323720961, G1420189321, Imaging Studies in Neurotoxicity and Neurodevelopment, Bioscience Research Infrastructure Development for Grant Enhancement and Success, G3864985968, Resource for Quantitative Functional FMRI, G43489937, Measuring Altered Glutathione in Children with Autism Spectrum Disorder, G4696009833, G4857246234, MR Techniques for Drug Abuse and HIV Brain Research, G678368552, G7439152590, G8931808009, Universal Edited MRS at 3T
OpenAlex ID: W3016864326