Year: 2020
Type: editorial
Abstract: Alterations in host defence functions of the airway epithelium play a central role in chronic airway diseases [1] by contributing to airway mucus obstruction, microbial dysbiosis and chronic airway inflammation. The contribution of altered epithelial functions to the pathogenesis of airway diseases is well illustrated in cystic fibrosis (CF), a monogenetic disease caused by inherited mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene [2]. Imbalances in neuropeptide-mediated regulation of airway gland serous cells may contribute to chronic airway diseases <http://bit.ly/2IGmcvU>
Source: European Respiratory Journal
Authors: Gimano D. Amatngalim, Carla M.P. Ribeiro
Language: English
Subfield: Pulmonary and Respiratory Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
OpenAlex ID: W3017052284