Work

HIV-1 infection and Fertility in Dar es Salaam, Tanzania / Infection du VIH-1 et fécondité à Dar es Salaam, Tanzanie

Year: 2006

Type: article

Abstract: The objective of this study was to examine the association of HIV-1 infection with rates of pregnancy and pregnancy loss in Dar es Salaam, Tanzania. A retrospective cohort study of 1,006 HIV-infected women and 485 uninfected women was employed. In multivariate analyses controlling for other predictors of pregnancy, the association of HIV-seropositivity with a woman's reported number of pregnancies was of borderline significance (RR = 1.13, 95% CI = 1.00, 1.27). HIV infection was not associated with pregnancy loss in multivariate analysis. The adjusted pregnancy rate ratio comparing HIV-positive women at the earliest stages of infection to all uninfected women was 1.22 (95% CI = 1.04, 1.42). HIV infection was not associated with female fertility when comparing women in the most advanced stages of infection to all uninfected women. We conclude that HIV-1 infected women had higher pregnancy rates than uninfected women. This association disappeared when analyses were limited to women with advanced disease. Abstract word count: 150.

Source: African Journal of Reproductive Health

DOI: 10.2307/30032470

Authors: Gilda Sedgh, Ulla Larsen, D. Spiegelman, Genard Msamanga, Wafaie W. Fawzi

Language: French

Topic: HIV/AIDS Research and Interventions

Subfield: Infectious Diseases

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

Funders: National Institutes of Health, U.S. Public Health Service, National Institute of Child Health and Human Development

Award: G1157234822