Work

Histidine Utilization Is a Critical Determinant of Acinetobacter Pathogenesis

Year: 2020

Type: article

Abstract: Acinetobacter baumannii is a nosocomial pathogen capable of causing a range of diseases, including respiratory and urinary tract infections and bacteremia. Treatment options are limited due to the increasing rates of antibiotic resistance, underscoring the importance of identifying new targets for antimicrobial development. During infection, A. baumannii must acquire nutrients for replication and survival. These nutrients include carbon- and nitrogen-rich molecules that are needed for bacterial growth.

Source: Infection and Immunity

DOI: 10.1128/iai.00118-20

Authors: Zachery R. Lonergan, Lauren D. Palmer, Eric P. Skaar

Institutions: Vanderbilt University, Vanderbilt University Medical Center

Language: English

Topic: Bacterial Genetics and Biotechnology

Subfield: Genetics

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funders: National Institutes of Health, National Heart, Lung, and Blood Institute, National Institute of Allergy and Infectious Diseases, National Institute of Diabetes and Digestive and Kidney Diseases