Work

Combined Omics Approach Identifies Gambogic Acid and Related Xanthones as Covalent Inhibitors of the Serine Palmitoyltransferase Complex

Year: 2020

Type: article

Source: Cell chemical biology

DOI: 10.1016/j.chembiol.2020.03.008

Authors: Dominic G. Hoch, Daniel Abegg, J. Thomas Hannich, Dany Pechalrieu, Anton Shuster, Brendan G. Dwyer, Chao Wang, Xiaojin Zhang, Qidong You, Howard Riezman, Alexander Adibekian

Institutions: University of Geneva, Scripps Research Institute, NCCR Chemical Biology - Visualisation and Control of Biological Processes Using Chemistry, China Pharmaceutical University

Language: English

Topic: Sphingolipid Metabolism and Signaling

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: bronze

Funders: National Science Foundation, Scripps Research Institute, Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung, NCCR Catalysis

OpenAlex ID: W3020642181

FWCI: 1.314

Cites: 96

Cited by: 28

Related to: 10