Work

Synthetic Lethality in Pediatric Brain Cancer Cells by Optimized PLGA Nanoparticles and Drug Combinations

Year: 2020

Type: article

Abstract: Here we test drugs effectiveness to inhibit various DNA repair pathways with the purpose of sensitizing cancer cells to radiotherapy. We work on optimizing delivery of DNA repair pathway inhibiting drugs by the use of PLGA nanoparticles.

Source: Lincoln (University of Nebraska)

Authors: Megan Ruckman, Megan Otte, Forrest M. Kievit

Language: English

Topic: Nanoparticle-Based Drug Delivery

Subfield: Biomaterials

Field: Materials Science

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W3021001630

FWCI:

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Related to: 10