Application of plasma circulating cell-free DNA detection to the molecular diagnosis of hepatocellular carcinoma.
Year: 2019
Type: article
Study design: Observational Study
Abstract: genes were significantly higher in patients with multiple tumors or with metastasis than in single tumor patients. In conclusion, amplicon sequencing technology is highly sensitive for the detection of mutant genes in the plasma cfDNA of HCC patients. Plasma cfDNA might be an effective molecular marker for HCC molecular diagnosis.
Source: Europe PMC (PubMed Central)
Institutions: Peking University People's Hospital, Second Affiliated Hospital of Xi'an Jiaotong University, Capital Medical University, Beijing Ditan Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Peking Union Medical College Hospital, Henan Cancer Hospital, Genecast (China)
Language: English
Subfield: Cancer Research
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W3021231684