Work

Amyloid beta accumulation in HIV-1 infected brain: the role of altered cholesterol homeostasis.

Year: 2014

Type: article

Abstract: synthesized apoE-cholesterol, apoB-containing LDL-cholesterol could lead to cholesterol accumulation thus disturbing neuronal endolysosome function and ultimately the accumulation of intraneuronal Aβ in HIV-1 infected brain.

Source: PubMed

Authors: Xuesong Chen, Liang Hui, Jonathan D Geiger

Institution: University of North Dakota

Language: English

Topic: Alzheimer's disease research and treatments

Subfield: Cellular and Molecular Neuroscience

Field: Neuroscience

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funders: National Institute on Aging, National Institute of Mental Health, National Institute of General Medical Sciences, National Institute of Neurological Disorders and Stroke

Awards: The role of novel endolysosome-dependent calcium regulatory mechanisms in HIV-1 T, COBRE Center for Neurodegenerative Disorder Research, Neuronal endolysosome involvement in HIV-1 Tat-induced amyloid beta accumulation, Ketogenic Diet and Adenosine: Epigenetics and Antiepileptogenesis

OpenAlex ID: W3021332243

FWCI: 0.252

Cites: 112

Cited by: 6

Related to: 10