Work

Protective benefits of AMP-activated protein kinase in hepatic ischemia-reperfusion injury.

Year: 2017

Type: article

Abstract: and the overproduction of reactive oxygen species (ROS) are also involved in the activation of AMPK during HIRI. The activated AMPK might provide protective benefits in HIRI via prevention of energy decline, inhibition of inflammatory response, suppression of hepatocyte apoptosis and attenuation of oxidative stress. Thus, AMPK might become a novel target for the pharmacological intervention of HIRI.

Source: PubMed Central

Authors: Min Zhang, Dan Yang, Xianqiong Gong, Pu Ge, Jie Dai, Ling Lin, Li Zhang

Institutions: Chongqing Medical University, Chongqing University of Arts and Sciences

Language: English

Topic: Organ Transplantation Techniques and Outcomes

Subfield: Surgery

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W3021389305

FWCI: 4.514

Cites: 67

Cited by: 38

Related to: 10