Work

Enantioselective S−H Insertion Reactions of α‐Carbonyl Sulfoxonium Ylides

Year: 2020

Type: article

Abstract: The first example of enantioselective S-H insertion reactions of sulfoxonium ylides is reported. Under the influence of thiourea catalysis, excellent levels of enantiocontrol (up to 95 % ee) and yields (up to 97 %) are achieved for 31 examples in S-H insertion reactions of aryl thiols and α-carbonyl sulfoxonium ylides.

Source: Angewandte Chemie International Edition

DOI: 10.1002/anie.202005563

Authors: Patrícia B. Momo, Alexandria N. Leveille, Elliot H. E. Farrar, Matthew N. Grayson, Anita E. Mattson, Antonio C. B. Burtoloso

Institutions: Instituto de Química de São Carlos, Worcester Polytechnic Institute, University of Bath

Language: English

Topic: Asymmetric Synthesis and Catalysis

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: hybrid

Estimated APC paid: $5,000