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Tibet Koyunlarında Büyüme Hormonunu Salgılatıcı Hormon (GHRH) Genindeki Polimorfizmlerin Büyüme Özellikleri İle İlişkisi

Year: 2019

Type: article

Abstract: The objectives of this study were to identify single nucleotide polymorphisms (SNPs) in the growth hormone-releasing hormone (GHRH) gene and to evaluate their associations with growth traits in two main Tibetan sheep breeds.Through sequencing technology, four SNPs were identified in the 5'UTR region of GHRH gene.Both g.794A>C and g.1497C>A exhibited significant influence on the growth-related traits in Tibetan sheep (P<0.05 or P<0.01).Hence, the biochemical and physiological functions, together with the results obtained in our investigation, suggest that the GHRH gene could serve as genetic marker for growth in Tibetan sheep breeding.

Source: Kafkas Universitesi Veteriner Fakultesi Dergisi

DOI: 10.9775/kvfd.2019.22522

Authors: Lin-Sheng GUI, Yang-Yang JIANG, Gui-Yao LIU, Jian-Lei JIA, Ming-De CHU, Sheng-Zhen HOU, Zhi-You WANG

Institutions: Qinghai University, State Key Laboratory of Plateau Ecology and Agriculture, Jiujiang University

Language: Turkish

Topic: Genetic and phenotypic traits in livestock

Subfield: Genetics

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Zero hunger

Open Access status: diamond

OpenAlex ID: W2971895677

FWCI: 0.132

Cites: 16

Cited by: 1

Related to: 10