Work

Minocycline Hepatotoxicity: Clinical characterization and identification of HLA-B* 35:02 as a risk factor

Year: 2017

Type: article

Abstract: Minocycline hepatotoxicity can present with prominent autoimmune features in previously healthy individuals. The aim of this study was to identify genetic determinants of minocycline DILI in a well-phenotyped cohort of patients.

Source: Carolina Digital Repository (University of North Carolina at Chapel Hill)

DOI: 10.17615/5gdw-gn33

Authors: Thomas Urban, Paola Nicoletti, Naga Chalasani, José Serrano, Andrew Stolz, Ann K. Daly, Guruprasad P. Aithal, John Dillon, Victor J. Navarro, Joseph A. Odin, Huiman X. Barnhart, David A. Ostrov, Nanye Long, Elizabeth T. Cirulli, Paul B. Watkins, Robert J. Fontana

Institutions: University of North Carolina at Chapel Hill, Columbia University, Indiana University School of Medicine, National Institute of Diabetes and Digestive and Kidney Diseases, University of Southern California, Newcastle University, Nottingham University Hospitals NHS Trust, University of Nottingham, National Institute for Health and Care Research, NIHR Nottingham Digestive Diseases Biomedical Research Unit, University of Dundee, Jefferson Einstein Philadelphia Hospital, Icahn School of Medicine at Mount Sinai, Duke University, University of Florida Health, University of Florida, University of Michigan

Language: English

Topic: Drug-Induced Hepatotoxicity and Protection

Subfield: Pharmacology

Field: Pharmacology, Toxicology and Pharmaceutics

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W3021877371

FWCI:

Cites:

Cited by: 2

Related to: 20