KSHV co-infection, a new co-factor for HPV-related cervical carcinogenesis?
Year: 2018
Type: article
Abstract: High-risk human papillomavirus (HPV) infection is the etiological agent of cervical cancer and some other cancers. Kaposi sarcoma-associated herpesvirus (KSHV) represents a principal causative agent of several human cancers arising in those immunocompromised patients. In fact, KSHV DNA has been detected in the female genital tract, and this virus may share some transmission routes with HPV, although the detection rate of KSHV in cervical samples is very low and the KSHV/HPV co-infection is seldom reported. Currently, it remains unclear about the role of KSHV co-infection in the development of HPV-related neoplasias. In this article, we have summarized the recent finding from clinic and bench indicating KSHV co-infection may represent a co-factor for the development of HPV-related carcinogenesis.
Source: Europe PMC (PubMed Central)
Language: English
Subfield: Oncology
Field: Medicine
Domain: Health Sciences
Open Access status: green
Awards: Periodontal bacteria enhance oral KSHV pathogenesis and Kaposi's Sarcoma development in HIV + patients, On the pathogenic role of anti-CD4 antibody in poor CD4+ T cell recovery after antiretroviral therapy in HIV disease, Synergistic effect of HIV virions and bacterial LPS on memory B cell apoptosis, Mentoring Translational Researchers in Louisiana, Louisiana Clinical and Translational Science Center, Center for Translational Viral Oncology (CTVO)
OpenAlex ID: W3022055879