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Differential contribution of metabotropic glutamate receptor 5 common allosteric binding site residues to biased allosteric agonism

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Year: 2020
Type: article
Source: Biochemical Pharmacology
DOI: 10.1016/j.bcp.2020.114011
Authors: Kathy Sengmany, Shane D. Hellyer, Arthur Christopoulos, David J. Lapinsky, Katie Leach, Karen J. Gregory
Institutions: Monash University, Duquesne University
Language: English

Topic: Neuroscience and Neuropharmacology Research
Subfield: Cellular and Molecular Neuroscience
Field: Neuroscience
Domain: Life Sciences
SDG: Good health and well-being

Open Access status: closed

Funders: Australian Research Council, National Health and Medical Research Council
Awards: Biased allosteric modulators of metabotropic glutamate receptors: novel therapeutic targets for CNS disorders, Exploring metabotropic glutamate receptor 5 bias, allostery and heteromers, Bias and allostery at the calcium sensing receptor, G4715820274, Enhancement of glutamate signalling as a novel approach to treat schizophrenia and cognitive disorders
OpenAlex ID: W3022370537
FWCI: 0.573
Cites: 44
Cited by: 9
Related to: 10
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