Sinecatechins Ointment, 15% for the Treatment of External Genital and Perianal Warts: Proceedings of an Expert Panel Roundtable Meeting.
Year: 2016
Type: article
Abstract: Sinecatechins ointment, 15% is a patient-applied prescription botanical treatment indicated for the topical treatment of external genital and perianal warts in immunocompetent patients 18 years and older. In two pivotal, randomized, double-blind, vehicle-controlled, Phase 3 studies, 53.6 percent of patients treated with sinecatechins ointment demonstrated complete clearance of baseline and newly emerging EGW, and 93.2 percent of these patients who achieved complete clearance of EGW experienced sustained clearance at 12 weeks post-treatment. In the vehicle group, 35.3 percent of patients had complete clearance, and 94.2 percent of these patients experienced sustained clearance at 12 weeks post-treatment.35 The most common side effects observed with sinecatechins ointment, 15% were mild-to-moderate local skin and application-site reactions, and the incidence of patients with local adverse events leading to discontinuation was 2.3 percent.35 The cases presented in this supplement are simulated and intended to represent patients who may be seen in clinical practice and demonstrate the role of sinecatechins ointment, 15% in the treatment of EGW. These patients do not represent any actual individual, and cases are intended to assist with clinical decision making only. The mechanism of action of sinecatechins ointment, 15% involved in the clearance of EGW is unknown and warrants further clinical and investigative studies.
Registered trademarks are the property of their respective owners.
VEREGEN® (sinecatechins) Ointment, 15% is indicated for the topical treatment of external genital and perianal warts (Condylomata acuminata) in immunocompetent patients 18 years and older. Important Safety Information: Avoid use of VEREGEN® on open wounds. See additional Important Safety Information on the following pages and Full PI at the end of the Supplement.
Source: Europe PMC (PubMed Central)
Language: English
Topic: Genital Health and Disease
Subfield: Surgery
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W2978718146