Work

A small molecule G6PD inhibitor reveals immune dependence on pentose phosphate pathway

Year: 2020

Type: article

Source: Nature Chemical Biology

DOI: 10.1038/s41589-020-0533-x

Authors: Jonathan M. Ghergurovich, Juan C. García-Cañaveras, Joshua Wang, Emily Schmidt, Zhaoyue Zhang, Tara TeSlaa, Harshel Patel, Li Chen, Emily C. Britt, Marta Piqueras-Nebot, Mari Carmen Gomez-Cabrera, Agustín Lahoz, Jing Fan, Ulf H. Beier, Hahn Kim, Joshua D. Rabinowitz

Institutions: Princeton University, University of Wisconsin–Madison, Morgridge Institute for Research, Instituto de Investigación Sanitaria La Fe, Universitat de València, Hospital Clínico Universitario de Valencia, Centro de Investigación Biomédica en Red de Fragilidad y Envejecimiento Saludable, Children's Hospital of Philadelphia, University of Pennsylvania

Language: English

Topic: Redox biology and oxidative stress

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funders: National Cancer Institute, National Institute of Diabetes and Digestive and Kidney Diseases

Awards: Metabolism in Action: Quantitative Fluxes in Mammals, Tumor cell metabolism in action

OpenAlex ID: W3022743377

FWCI: 8.022

Cites: 56

Cited by: 211

Related to: 10