Work

Tumor microenvironment-activatable Fe-doxorubicin preloaded amorphous CaCO 3 nanoformulation triggers ferroptosis in target tumor cells

Year: 2020

Type: article

Abstract: This study describes a ferroptosis/apoptosis-based treatment strategy via the cooperation between Fe 2+ and doxorubicin.

Source: Science Advances

DOI: 10.1126/sciadv.aax1346

Authors: Chen-Cheng Xue, Meng-Huan Li, Yang Zhao, Jun Zhou, Yan Hu, Kai-Yong Cai, Yanli Zhao, Shu-Hong Yu, Zhong Luo

Institutions: Chongqing University, University of Science and Technology of China, Nanyang Technological University, Collaborative Innovation Center of Suzhou Nano Science and Technology

Language: English

Topic: Nanoplatforms for cancer theranostics

Subfield: Biomedical Engineering

Field: Engineering

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $4,500

Funders: National Natural Science Foundation of China, National Key Research and Development Program of China, Fundamental Research Funds for the Central Universities

Awards: 共载化疗药物/siRNA可降解介孔硅递送系统有序靶向逆转乳腺癌耐药性及机制研究, G1287417319, G1578082783, G1767487279, 轻质、抗疲劳纳米结构单元组装弹性体的构筑和应用研究, G6253425530, G8362881974, 共载化疗药物/光敏剂的脂质体复合递送系统联合逆转黑色素瘤耐药性及机制研究

OpenAlex ID: W3022794030

FWCI: 13.45

Cites: 56

Cited by: 306

Related to: 9