Serum NOX2 as a new biomarker candidate for HBV-related disorders.
Year: 2018
Type: article
Study design: Observational Study
Abstract: < 0.01) and that the levels of serum NOX2 were significantly correlated with the serum levels of superoxide dismutase (SOD), interleukin-6 (IL-6), interferon-stimulated gene 15 (ISG15), alkaline phosphatase (ALP) and gamma glutamyl transpeptidase (GGT) in chronic hepatitis B, cirrhosis and hepatocellular carcinoma patients. Interestingly, we found that a significant positive correlation between NOX2 and HBV viral load only in patients with chronic hepatitis B and cirrhosis. Therefore, Serum NOX2 levels maybe an important indicator of the pathogenesis of progression of HBV-related disorders.
Source: Europe PMC (PubMed Central)
Authors: Yuan Xiong, Yuanyuan Ye, Pu Li, Yahui Xiong, Jinju Mao, Yong Huang, Weixian Chen, Bo Wang
Language: English
Topic: Hepatitis B Virus Studies
Subfield: Epidemiology
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W3023053370