Work

Depression and coronary artery disease: the association, mechanisms, and therapeutic implications.

Year: 2009

Type: article

Abstract: We performed a comprehensive review of the literature to determine whether or not a relationship between depression and coronary artery disease exists. Our literature search supports the following: Depression and coronary artery disease have a bidirectional relationship, i.e., coronary artery disease can cause depression and depression is an independent risk factor for coronary artery disease and its complications; depression may contribute to sudden cardiac death and increase all causes of cardiac mortality; and depression contributes to unhealthy lifestyle and poor adherence to treatment. We review various pathophysiological links between depression and coronary artery disease and screening for depression in at-risk patients for coronary artery disease. We also discuss pharmacological treatments, their implications, and various behavioral treatments.

Source: PubMed Central

Authors: Imran Shuja Khawaja, Joseph J Westermeyer, Prashant Gajwani, Robert E Feinstein

Institutions: University of Minnesota, Mayo Clinic, Case Western Reserve University, University of Colorado Denver

Language: English

Topic: Cardiac Health and Mental Health

Subfield: Cardiology and Cardiovascular Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W3024201994

FWCI: 4.244

Cites: 131

Cited by: 195

Related to: 10