Work

The Association of Whole Grain Intake and Fasting Insulin in a Biracial Cohort of Young Adults: The CARDIA Study.

Year: 1998

Type: article

Abstract: BACKGROUND: Whole grain consumption may influence insulin through beneficial effects on satiety and body weight, intestinal absorption, or the action of specific nutrients or constituents. DESIGN AND METHODS: We examined the associations of whole grain intake, assessed by a diet history interview at baseline (year 0) and year 7, with body mass index (BMI), waist-hip ratio (WHR), and fasting insulin in 3,627 Black and White adults in the Coronary Artery Risk Development in Young Adults Study (CARDIA). We estimated year 0 and year 7 cross-sectional associations accounting for correlation between years using repeated measures regression. RESULTS: U/mL in Black men, white men, and white women, respectively (p < 0.05). The inverse association of whole grain intake and fasting insulin remained significant (p < 0.05) after adjustment for body mass index. Potentially mediating nutrients explaining part of the relationship between whole grain intake and fasting insulin were dietary magnesium and fiber. CONCLUSIONS: The independent inverse relationship between whole grain consumption and fasting insulin levels may have important public health implications in light of the low consumption of whole grains and the increasing prevalence of obesity and diabetes in the US.

Source: PubMed