Work

Epigenetic Mechanisms in Multiple Sclerosis.

Year: 2014

Type: article

Abstract: The interplay between genetic factors and cell-specific epigenetic changes may be highly relevant in development of multiple sclerosis (MS). Environmental risk factors for MS are able to modify the epigenome, constituting a link between environment exposure and changes in gene expression. In this review we discuss the most relevant epigenetic findings described in different tissues from MS patients and the future application of epigenetic advances in MS field.

Source: PubMed

Authors: Mar Gacias, Patrizia Casaccia

Institution: Icahn School of Medicine at Mount Sinai

Language: English

Topic: Multiple Sclerosis Research Studies

Subfield: Clinical Neurology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funder: National Institute of Neurological Disorders and Stroke

Awards: Histone Deacetylation in Oligodendrocyte Differentiation, Mechanism of regulation of progenitor proliferation and transformation, Molecular Mechanism of Neuronal Damage in Demyelinating Disorders