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Inhibitor design to target a unique feature in the folate pocket of Staphylococcus aureus dihydrofolate reductase

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Year: 2020
Type: article
Source: European Journal of Medicinal Chemistry
DOI: 10.1016/j.ejmech.2020.112412
Authors: N. Prasad Muddala, John C. White, Baskar Nammalwar, Ian Pratt, Leonard M. Thomas, Richard A. Bunce, K. Darrell Berlin, Christina R. Bourne
Institutions: Oklahoma State University, University of Oklahoma
Language: English

Topic: Antimicrobial Resistance in Staphylococcus
Subfield: Infectious Diseases
Field: Medicine
Domain: Health Sciences
SDG: Good health and well-being

Open Access status: bronze

Funders: National Science Foundation, W. M. Keck Foundation, ConocoPhillips, Oklahoma State University, University of Oklahoma, College of Arts and Sciences, Oklahoma State University, National Institutes of Health, National Institute of General Medical Sciences, National Institute of Allergy and Infectious Diseases
Awards: Acquisition of Instrumentation for an Oklahoma Statewide Shared NMR Facility, Broad-spectrum Antifolates for Treatment of Drug Resistant Bacillus anthracis, Oklahoma COBRE in Structural Biology, MRI: Acquisition of Robotics Instrumentation for Crystallization of Biomacromolecules
OpenAlex ID: W3028541477
FWCI: 0.131
Cites: 44
Cited by: 9
Related to: 10
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