Work

Immunohistochemical analysis of SLFN11 expression uncovers potential non-responders to DNA-damaging agents overlooked by tissue RNA-seq

Year: 2020

Type: article

Study design: Observational Study

Source: Archiv für Pathologische Anatomie und Physiologie und für Klinische Medicin

DOI: 10.1007/s00428-020-02840-6

Authors: Tsuyoshi Takashima, Naoya Sakamoto, Junko Murai, Daiki Taniyama, Ririno Honma, Shoichi Ukai, Ryota Maruyama, Kazuya Kuraoka, Vinodh N. Rajapakse, Yves Pommier, Wataru Yasui

Institutions: Hiroshima University, Keio University, National Hospital Organization, Kure Medical Center, National Institutes of Health, National Cancer Institute, Center for Cancer Research

Language: English

Topic: Cancer therapeutics and mechanisms

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funders: National Institutes of Health, Japan Society for the Promotion of Science, National Cancer Institute

Awards: Role of Non-coding RNA of T-UCR in exosome in diagnosis and therapy of gastric and prostatic cancer, Search for new therapeutic target against cancer stem cells using intestinal-/gastric type gastric cancer organoid, Histologial diversity and T-UCR mechansm of gastrointestinal cancer, and their application to clinical practice, Secretory Transcribed-ultraconserved regions in gastrointestinal and urological cancers and their application to liquid biopsy, Establishment of the model of intestinal and gastric type gastric cancer using CRISPR/Cas9 and organoid, Development of SLFN11 as a tumor supressor gene, Identification and clinical application of diagnostic and therapeutic marker of esophageal and gastric cancer targeting cancer stem cell, G9000173957, DNA Repair, Cell Cycle Checkpoints and Apoptosis as Targets for Anticancer Drugs

OpenAlex ID: W3029013190

FWCI: 1.728

Cites: 23

Cited by: 54

Related to: 10