Work

Synthesis and characterization of novel biological tetracoumarin derivatives bearing ether moieties

Year: 2020

Type: article

Abstract: A series of novel tetracoumarin derivatives ( 3a-f ) were prepared using the reaction of ether functionalized dibenzaldehyde with 4-hydroxycoumarin in the presence of sodium acetate. The structure of compounds was validated by IR, NMR, and CHN analyzes. Antimicrobial (antibacterial and antifungal) activity was studied on the basis of the minimum bactericidal concentration, minimum inhibitory concentration and inhibitory zone diameter. Favorable biological activity was found in compound 3f .

Source: Heterocyclic Communications

DOI: 10.1515/hc-2020-0009

Authors: Soheila Asadpour Behzadi, Enayatollah Sheikhhosseini, Sayed Ali Ahmadi, Dadkhoda Ghazanfari, Mohammadreza Akhgar

Institution: Islamic Azad University Kerman

Language: English

Topic: Synthesis and biological activity

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,808