The determination of anti-mullerian hormone and vitamin D serum levels in polycystic ovary syndrome
Year: 2020
Type: article
Study design: Observational Study
Abstract: Aim: This study aimed to determine whether there is a relationship between serum anti-mullerian hormone (AMH) and vitamin D levels and the severity of polycystic ovary syndrome (PCOS).Material and method: Forty-four women with PCOS and forty-four controls with regular ovulatory menstrual cycles were included in this study between February 2016 and November 2016.Hormonal parameters, glucose metabolism parameters, clinical signs, and symptoms and serum AMH and vitamin D levels were determined.Results: AMH levels, hirsutism scores, and postprandial glucose levels were significantly different between the two groups.There were statistically significant positive correlations between AMH and luteinizing hormone (LH)/follicle stimulating hormone (FSH) ratio, homeostatic model assessment of insulin resistance (HOMA-IR), fasting glucose levels, and hirsutism scores.Serum AMH levels were significantly higher in women with PCOS compared to controls.The levels of vitamin D were found low in both groups, and there was no statistically significant difference between the two groups in vitamin D levels.Conclusion: There were positive correlations between AMH levels and LH/FSH ratio, hirsutism scores, HOMA-IR, and the fasting insulin.The patients with higher AMH levels were more hyperandrogenic compared to patients with PCOS who have lower AMH levels.Nevertheless, there was no statistically significant difference between the two groups in vitamin D levels.
Source: DergiPark (Istanbul University)
Authors: Senem Arda Düz, Görkem Tuncay, Abdullah Karaer
Institution: Inonu University
Language: English
Subfield: Reproductive Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W3031057192