Work

PROteolysis TArgeting Chimeras (PROTACs) as emerging anticancer therapeutics

Year: 2020

Type: review

Source: Oncogene

DOI: 10.1038/s41388-020-1336-y

Authors: Sajid Khan, Yonghan He, Xuan Zhang, Yaxia Yuan, Shaoyan Pu, Qingpeng Kong, Guangrong Zheng, Daohong Zhou

Institutions: University of Florida, Kunming Institute of Zoology, Chinese Academy of Sciences, State Key Laboratory of Genetic Resources and Evolution

Language: English

Topic: Protein Degradation and Inhibitors

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funders: U.S. Department of Health and Human Services, National Cancer Institute

Awards: G154005219, G201614453, Role of Senescent Cells in Radiation-induced Pulmonary Fibrosis, G2496244344, NCI Clinical and Translational Exploratory/ Developmental Studies, Ionizing radiation induced hematological malignancies, G3811368727, Use of BCL-xL Proteolysis targeting chimeras to treat pancreatic cancer

OpenAlex ID: W3031903798

FWCI: 3.51

Cites: 111

Cited by: 255

Related to: 10