Work

Compound A inhibits urothelial tumorigenesis via both the androgen receptor and glucocorticoid receptor signaling pathways.

Year: 2020

Type: article

Abstract: activation of glucocorticoid-response element-mediated transcription and expression of its targets) in SVHUC cells. These findings suggest that CpdA suppresses urothelial tumorigenesis via both the AR and GR pathways, which may consequently provide an effective option of chemoprevention for bladder cancer, especially in patients with superficial disease following transurethral surgery.

Source: PubMed

Authors: Hiroki Ide, Satoshi Inoue, Taichi Mizushima, Guiyang Jiang, Yujiro Nagata, Takuro Goto, Eiji Kashiwagi, Hiroshi Miyamoto

Institutions: Johns Hopkins University, Johns Hopkins Medicine, University of Rochester Medicine, University of Rochester

Language: English

Topic: Bladder and Urothelial Cancer Treatments

Subfield: Surgery

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W3033986370

FWCI: 0.9

Cites: 29

Cited by: 6

Related to: 10