Work

Antiulcerogenic and anti-inflammatory effects of emodin, isolated from Rhamnus triquerta wall.

Year: 1991

Type: article

Abstract: Emodin, an anthraquinone derivative, isolated from the whole plant of R. triquerta, in 15 mg/kg dose (ip) exhibited anti-inflammatory activity against carrageenin-induced pedal inflammation in rats. In the same dosage it also showed antiulcer activity against 4 hr pylorus-ligated, aspirin and immobilization stress-induced gastric ulcers in rats. It decreased acid and pepsin output and augmented mucus secretion in terms of total carbohydrate: protein ratio in the gastric juice of aspirin treated pylorus-ligated rats, indicating that the antiulcerogenic effect of emodin may be due to its effect on gastric secretion.

Source: PubMed

Authors: R K Goel, G Das Gupta, S N Ram, V B Pandey

Institution: Banaras Hindu University

Language: English

Topic: Phytochemistry and biological activity of medicinal plants

Subfield: Plant Science

Field: Agricultural and Biological Sciences

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W30343921

FWCI:

Cites: 35

Cited by: 45

Related to: 10