Year: 2020
Type: article
Abstract: Cancers that arise in the head and neck region are comprised of a heterogeneous group of malignancies that include carcinogen- and human papillomavirus (HPV)-driven mucosal squamous cell carcinoma as well as skin cancers such as cutaneous squamous cell carcinoma, basal cell carcinoma, melanoma, and Merkel cell carcinoma. These malignancies develop in critical areas for eating, talking, and breathing and are associated with substantial morbidity and mortality despite advances in treatment. Understanding of advances in the management of these various cancers is important for all multidisciplinary providers who care for patients across the cancer care continuum. Additionally, the recent Coronavirus Disease 2019 (COVID-19) pandemic has necessitated adaptations to head and neck cancer care to accommodate the mitigation of COVID-19 risk and ensure timely treatment. This review explores advances in diagnostic criteria, prognostic factors, and management for subsites including head and neck squamous cell carcinoma and the various forms of skin cancer (basal cell carcinoma, cutaneous squamous cell carcinoma, Merkel cell carcinoma, and melanoma). Then, this review summarizes emerging developments in immunotherapy, radiation therapy, cancer survivorship, and the delivery of care during the COVID-19 era.
Source: Cancers
Language: English
Topic: Head and Neck Cancer Studies
Subfield: Otorhinolaryngology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $2,324
Awards: Determining mechanisms of enhanced antitumor efficacy of four-day expanded Th17 cells for adoptive transfer, G3410771321, Improving the Timeliness and Equity of Adjuvant Therapy Following Surgery for Head and Neck Cancer, G4470477270, The tumor suppressor capability of p53 is dependent on Non-muscle Myosin IIA function in Head and Neck Cancer., TRAINING PROGRAM FOR MEDICAL SCIENTISTS, G5959984393, G6380870836, T-COHR: Training in Craniofacial and Oral Health Research, Ceramide Signaling in the Regulation of Head & Neck Cancer Cell Death and Therapy
OpenAlex ID: W3034572983