Mechanisms of increased vascular stiffness down the aortic tree in aging, premenopausal female monkeys
Year: 2020
Type: article
Abstract: This is the first study to examine vascular stiffness down the aortic tree in aging premenopausal females (24 ± 0.7 yr old), whereas prior work studied mainly rodents, which are short-lived and do not undergo menopause. Histological mechanisms mediating vascular stiffness in older premenopausal females increased progressively down the aortic tree, with greater increases in the abdominal aorta compared with the thoracic aorta and with the greatest increases and differences observed in the iliac artery.
Language: English
Subfield: Cardiology and Cardiovascular Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
Awards: Angiogenesis Protection Induced by sFRP3 Myocyte/Vascular Cross-Talk, SFRP2, cell survival, and coronary vascular angiogenesis, Skeletal Muscle and Brown Adipose Mechanisms Mediating Cardiovascular Risk Factor Protection in RGS14 KO, Vascular Protection in Hibernating Woodchucks, RGS 14 Disruption, Vascular Effects Leading to Cardioprotection, INHIBITION OF ADENYLYL CYCLASE TYPE 5: HEALTHFUL AGING PROTECTION, Intrinsic Vascular Smooth Muscle Cell Stiffness, Skeletal Muscle Basis for Improved Exercise Endurance in RGS14 KO, Emory National Primate Research Center
OpenAlex ID: W3034672722