Work

Dihydroxyacetone phosphate signals glucose availability to mTORC1

Year: 2020

Type: article

Source: Nature Metabolism

DOI: 10.1038/s42255-020-0250-5

Authors: Jose M. Orozco, Patrycja A. Krawczyk, Sonia M. Scaria, Andrew L. Cangelosi, Sze Ham Chan, Tenzin Kunchok, Caroline A. Lewis, David M. Sabatini

Institutions: Broad Institute, Howard Hughes Medical Institute, Whitehead Institute for Biomedical Research, Koch Institute for Integrative Cancer Research At MIT, Massachusetts Institute of Technology

Language: English

Topic: PI3K/AKT/mTOR signaling in cancer

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: green

Funders: Howard Hughes Medical Institute, U.S. Department of Health and Human Services, American Cancer Society, National Institutes of Health, National Cancer Institute, National Institute of General Medical Sciences, National Institute of Allergy and Infectious Diseases, National Institute of Diabetes and Digestive and Kidney Diseases

Awards: G3281679040, G3444993983, Medical Scientist Training Program, Leucine Sensing by the mTORC1 Pathway in the Liver, G4666494287, Regulation of the mTOR Pathway by Nutrients, Novel Components of the mTORC1 and mTORC2 Pathways, Cell Growth Signaling in Cancer Development, Pre-Doctoral Training in Biological Sciences, G7542484234, Determining the mechanism of aspartate sensing by the mTOR pathway, Novel Components of the mTORC1 and mTORC2 Pathways, G9000140178

OpenAlex ID: W3044495713

FWCI: 11.11

Cites: 44

Cited by: 247

Related to: 10