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Monogenic and polygenic inheritance become instruments for clonal selection

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Year: 2020
Type: article
Source: Nature
DOI: 10.1038/s41586-020-2430-6
Authors: Po-Ru Loh, Giulio Genovese, Steven A. McCarroll
Institutions: Broad Institute, Brigham and Women's Hospital, Harvard University, Stanley Center for Psychiatric Research
Language: English

Topic: Acute Myeloid Leukemia Research
Subfield: Hematology
Field: Medicine
Domain: Health Sciences
SDG: Good health and well-being

Open Access status: green

Funders: U.S. Department of Defense, Glenn Foundation for Medical Research, Wellcome Trust, Broad Institute, Vrije Universiteit Amsterdam, Fondation pour la Recherche Médicale, Nederlandse Organisatie voor Wetenschappelijk Onderzoek, National Institutes of Health, Medical Research Council, National Human Genome Research Institute, National Institute of Environmental Health Sciences
Awards: G1151563582, G16286648, Structurally complex genome loci in human populations and human phenotypes, G21146293, G2156109490, G4119534169, EXAMINING THE ROLE OF CHROMOSOMAL INSTABILITY IN BREAST CANCER EVOLUTION, Multi-allelic forms of human genome structural variation, UK Biobank (core renewal), G5850682332, Revealing somatic genome alterations and their clinical sequelae: Ultrasensitive computational detection of mosaic structural variants
OpenAlex ID: W3037260227
FWCI: 15.8
Cites: 78
Cited by: 204
Related to: 10
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