Work

Anti-apoptotic BCL-2 family proteins confer resistance to calicheamicin-based antibody-drug conjugate therapy of acute leukemia

Year: 2020

Type: article

Abstract: Over 26,000 people will face a new diagnosis of acute myeloid leukemia (AML) or acute lymphoblastic leukemia (ALL) in 2020 in the U.S. alone, and only a minority will be long-term survivors [1]. Am...

Source: Leukemia & lymphoma/Leukemia and lymphoma

DOI: 10.1080/10428194.2020.1786553

Authors: Colin D. Godwin, Olivia M. Bates, Sae Rin Jean, George S. Laszlo, Eliotte E. Garling, Mary E. Beddoe, Michael H. Cardone, Roland B. Walter

Institutions: University of Washington, Fred Hutch Cancer Center, Eutropics Pharmaceuticals (United States)

Language: English

Topic: Cell death mechanisms and regulation

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funders: Leukemia and Lymphoma Society, National Institutes of Health, National Heart, Lung, and Blood Institute, National Cancer Institute

Awards: G3449718282, G4780839780, G478348611, G834931733, Cancer Center Support Grant

OpenAlex ID: W3038270271

FWCI: 0.484

Cites: 14

Cited by: 15

Related to: 10