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Why continuing uncertainties are no reason to postpone challenge trials for coronavirus vaccines

Year: 2020

Type: article

Abstract: To counter the pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), some have proposed accelerating SARS-CoV-2 vaccine development through controlled human infection (or 'challenge') trials. These trials would involve the deliberate exposure of relatively few young, healthy volunteers to SARS-CoV-2. We defend this proposal against the charge that there is still too much uncertainty surrounding the risks of COVID-19 to responsibly run such a trial.

Source: Journal of Medical Ethics

DOI: 10.1136/medethics-2020-106501

Authors: Robert Steel, Lara Buchak, Nir Eyal

Institutions: Rutgers, The State University of New Jersey, Princeton University

Language: English

Topic: Ethics in Clinical Research

Subfield: Public Health, Environmental and Occupational Health

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Funders: Open Philanthropy Project, National Institute of Allergy and Infectious Diseases